Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood–Brain Barrier

Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood–Brain Barrier

The blood–brain barrier (BBB) is a highly selective cellular barrier that tightly controls the microenvironment of the central nervous system to restrict the passage of substances, which is a primary challenge in delivering therapeutic drugs to treat brain diseases. This study aimed to develop simpl...

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Bibliographic Details
Main Authors: Yi-Ping Chen, Chih-Ming Chou, Tsu-Yuan Chang, Hao Ting, Julien Dembélé, You-Tai Chu, Tsang-Pai Liu, Chun A. Changou, Chien-Wei Liu, Chien-Tsu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Chemistry
Subjects:
blood–brain barrier
mesoporous silica nanoparticles
zebrafish
doxorubicin
protein corona
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.931584/full

Internet

https://www.frontiersin.org/articles/10.3389/fchem.2022.931584/full

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