18F-FDG-PET-based Radiomics signature predicts MGMT promoter methylation status in primary diffuse glioma

18F-FDG-PET-based Radiomics signature predicts MGMT promoter methylation status in primary diffuse glioma

Abstract Background The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter has emerged as a favorable independent prognostic and predictive biomarker in glioma. This study aimed to build a radiomics signature based on 18F-fluorodeoxyglucose (FDG) positron emission tomog...

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Bibliographic Details
Main Authors: Ziren Kong, Yusong Lin, Chendan Jiang, Longfei Li, Zehua Liu, Yuekun Wang, Congxin Dai, Delin Liu, Xuying Qin, Yu Wang, Zhenyu Liu, Xin Cheng, Jie Tian, Wenbin Ma
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cancer Imaging
Subjects:
Radiomics
FDG PET
MGMT promoter methylation
Glioma
Prognosis
Online Access:http://link.springer.com/article/10.1186/s40644-019-0246-0

Internet

http://link.springer.com/article/10.1186/s40644-019-0246-0

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