Effective Preparation of [<sup>18</sup>F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor

Effective Preparation of [<sup>18</sup>F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor

(1) Background: [<sup>18</sup>F]Flumazenil <b>1</b> ([<sup>18</sup>F]FMZ) is an established positron emission tomography (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABA<sub>A</sub> in the brain. The produc...

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Bibliographic Details
Main Authors: Mohammad B. Haskali, Peter D. Roselt, Terence J. O’Brien, Craig A. Hutton, Idrish Ali, Lucy Vivash, Bianca Jupp
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
radiofluorination
PET imaging
GABA<sub>A</sub>
radiochemistry
Flumazenil 1
benzodiazepine
Online Access:https://www.mdpi.com/1420-3049/27/18/5931

Internet

https://www.mdpi.com/1420-3049/27/18/5931

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