Behavioral Evaluation of Hemiparkinsonian MPTP Monkeys following Dopamine Pharmacological Manipulation and Adrenal Co-Graft Transplantation

Bradykinesia and rigidity are the symptoms that most directly correlate with loss of striatal dopamine in Parkinson's disease. In the hemiparkinsonian (HP) monkey, this is represented by paucity of movement as measured by computerized movement analysis, diminished manual dexterity on clinical e...

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Bibliographic Details
Main Authors: Leonard L. Howell Ph.D., Larry D. Byrd, Ann M. Mcdonough, P. Michael Iuvone, Roy A. E. Bakay
Format: Article
Language:English
Published: SAGE Publishing 2000-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970000900506