Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion

Nc886, a Novel Suppressor of the Type I Interferon Response Upon Pathogen Intrusion

Interferons (IFNs) are a crucial component in the innate immune response. Especially the IFN-β signaling operates in most cell types and plays a key role in the first line of defense upon pathogen intrusion. The induction of IFN-β should be tightly controlled, because its hyperactivation can lead to...

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Bibliographic Details
Main Authors: Yeon-Su Lee, Xiaoyong Bao, Hwi-Ho Lee, Jiyoung Joan Jang, Enkhjin Saruuldalai, Gaeul Park, Wonkyun Ronny Im, Jong-Lyul Park, Seon-Young Kim, Sooyong Shin, Sung Ho Jeon, Sangmin Kang, Hyun-Sung Lee, Ju-Seog Lee, Ke Zhang, Eun Jung Park, In-Hoo Kim, Yong Sun Lee
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
nc886
pathogen
interferon
Protein Kinase R
Interferon Regulatory Factor 3
Online Access:https://www.mdpi.com/1422-0067/22/4/2003

Internet

https://www.mdpi.com/1422-0067/22/4/2003

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