Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus

Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus

Thymic epithelial cells (TECs) are critical for T cell development and self-tolerance but are gradually lost with age. The existence of thymic epithelial progenitors (TEPCs) in the postnatal thymus has been inferred, but their identity has remained enigmatic. Here, we assessed the entire adult TEC c...

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Bibliographic Details
Main Authors: Kahlia Wong, Natalie L. Lister, Marco Barsanti, Joanna M.C. Lim, Maree V. Hammett, Danika M. Khong, Christopher Siatskas, Daniel H.D. Gray, Richard L. Boyd, Ann P. Chidgey
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714006135

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http://www.sciencedirect.com/science/article/pii/S2211124714006135

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