Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation

Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation

Protein inhibitor of activated STAT (PIAS) proteins are activation-suppressing proteins for signal transducer and activator of transcription (STAT), which involves gene transcriptional regulation. The inhibitory mechanism of PIAS proteins in the Janus kinase (JAK)/STAT signaling pathway has been wel...

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Bibliographic Details
Main Authors: Guo-Juan Niu, Ji-Dong Xu, Wen-Jie Yuan, Jie-Jie Sun, Ming-Chong Yang, Zhong-Hua He, Xiao-Fan Zhao, Jin-Xing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
protein inhibitor of activated STAT
signal transducer and activator of transcription
signaling pathway
antimicrobial peptide
Marsupenaeus japonicus
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02392/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02392/full

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