Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy

Efficient Radial-Shell Model for 3D Tumor Spheroid Dynamics with Radiotherapy

Understanding the complex dynamics of tumor growth to develop more efficient therapeutic strategies is one of the most challenging problems in biomedicine. Three-dimensional (3D) tumor spheroids, reflecting avascular microregions within a tumor, are an advanced in vitro model system to assess the cu...

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Bibliographic Details
Main Authors: Florian Franke, Soňa Michlíková, Sebastian Aland, Leoni A. Kunz-Schughart, Anja Voss-Böhme, Steffen Lange
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cancers
Subjects:
spheroids
spatio-temporal mathematical modelling
cellular automaton
radial shell model
growth curve
3D growth
Online Access:https://www.mdpi.com/2072-6694/15/23/5645

Internet

https://www.mdpi.com/2072-6694/15/23/5645

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