Sinomenine Inhibits Migration and Invasion of Human Lung Cancer Cell through Downregulating Expression of miR-21 and MMPs

Sinomenine Inhibits Migration and Invasion of Human Lung Cancer Cell through Downregulating Expression of miR-21 and MMPs

Sinomenine is an alkaloid derived from <i>Sinomenium acutum</i>. Recent studies have found that sinomenine can inhibit various cancers by inhibiting the proliferation, migration and invasion of tumors and inducing apoptosis. This study aims to investigate the effect and mechanism of sino...

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Bibliographic Details
Main Authors: Kun-Hung Shen, Jui-Hsiang Hung, Yi-Ching Liao, Shu-Ting Tsai, Ming-Jiuan Wu, Pin-Shern Chen
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
sinomenine
lung cancer
cell invasion
matrix metalloproteinase
microRNA-21
Online Access:https://www.mdpi.com/1422-0067/21/9/3080

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https://www.mdpi.com/1422-0067/21/9/3080

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