IgG immune complex-induced acute lung injury is ameliorated by cAMP via down-regulation of C/EBP- and AP-1-mediated transcriptions

Abstract Background Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) are life threatening pulmonary diseases, and we are now lack of effective therapeutic methods. Inflammatory responses are essential for initiating ALI/ARDS. Thus, ameliorating inflammator...

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Bibliographic Details
Main Authors: Chunguang Yan, Jing Chen, Huifang Tang, Chunmin Deng, Qi Zhang, Ximo Wang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Inflammation
Subjects:
Online Access:https://doi.org/10.1186/s12950-023-00359-6