Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors.

Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors.

<h4>Introduction</h4>Lassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear.<h4>Methods</h4>We investigated Lassa virus specific CD8+ T cell responses in 9...

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Bibliographic Details
Main Authors: Stephanie M LaVergne, Saori Sakabe, Mambu Momoh, Lansana Kanneh, Nell Bond, Robert F Garry, Donald S Grant, Juan Carlos de la Torre, Michael B A Oldstone, John S Schieffelin, Brian M Sullivan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010882

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https://doi.org/10.1371/journal.pntd.0010882

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