Patterned Arteriole-Scale Vessels Enhance Engraftment, Perfusion, and Vessel Branching Hierarchy of Engineered Human Myocardium for Heart Regeneration

Patterned Arteriole-Scale Vessels Enhance Engraftment, Perfusion, and Vessel Branching Hierarchy of Engineered Human Myocardium for Heart Regeneration

Heart regeneration after myocardial infarction (MI) using human stem cell-derived cardiomyocytes (CMs) is rapidly accelerating with large animal and human clinical trials. However, vascularization methods to support the engraftment, survival, and development of implanted CMs in the ischemic environm...

Full description

Bibliographic Details
Main Authors: Rajeev J. Kant, Kiera D. Dwyer, Jang-Hoon Lee, Collin Polucha, Momoka Kobayashi, Stephen Pyon, Arvin H. Soepriatna, Jonghwan Lee, Kareen L. K. Coulombe
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
inosculation
vascularization
hiPSC-derived cardiomyocytes
patterned vessels
engineered cardiac tissue
heart regeneration
Online Access:https://www.mdpi.com/2073-4409/12/13/1698

Internet

https://www.mdpi.com/2073-4409/12/13/1698

Similar Items