A functional personalised oncology approach against metastatic colorectal cancer in matched patient derived organoids

Abstract Globally, colorectal cancer (CRC) is the third most frequently occurring cancer. Progression on to an advanced metastatic malignancy (metCRC) is often indicative of poor prognosis, as the 5-year survival rates of patients decline rapidly. Despite the availability of many systemic therapies...

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Main Authors: Dexter Kai Hao Thng, Lissa Hooi, Bei En Siew, Kai-Yin Lee, Ian Jse-Wei Tan, Bettina Lieske, Norman Sihan Lin, Alfred Wei Chieh Kow, Shi Wang, Masturah Bte Mohd Abdul Rashid, Chermaine Ang, Jasmin Jia Min Koh, Tan Boon Toh, Ker-Kan Tan, Edward Kai-Hua Chow
格式: 文件
语言:English
出版: Nature Portfolio 2024-02-01
丛编:npj Precision Oncology
在线阅读:https://doi.org/10.1038/s41698-024-00543-8