Citrullination of glucokinase is linked to autoimmune diabetes

Post translational modifications are involved in the regulation of a number of proteins and can be themselves modified by the cellular environment. Here the authors implicate citrullination of glucokinase in autoimmune diabetes

Bibliographic Details
Main Authors: Mei-Ling Yang, Sheryl Horstman, Renelle Gee, Perrin Guyer, TuKiet T. Lam, Jean Kanyo, Ana L. Perdigoto, Cate Speake, Carla J. Greenbaum, Aïsha Callebaut, Lut Overbergh, Richard G. Kibbey, Kevan C. Herold, Eddie A. James, Mark J. Mamula
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-29512-0