Citrullination of glucokinase is linked to autoimmune diabetes
Post translational modifications are involved in the regulation of a number of proteins and can be themselves modified by the cellular environment. Here the authors implicate citrullination of glucokinase in autoimmune diabetes
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-04-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-29512-0 |
| _version_ | 1811272601782190080 |
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| author | Mei-Ling Yang Sheryl Horstman Renelle Gee Perrin Guyer TuKiet T. Lam Jean Kanyo Ana L. Perdigoto Cate Speake Carla J. Greenbaum Aïsha Callebaut Lut Overbergh Richard G. Kibbey Kevan C. Herold Eddie A. James Mark J. Mamula |
| author_facet | Mei-Ling Yang Sheryl Horstman Renelle Gee Perrin Guyer TuKiet T. Lam Jean Kanyo Ana L. Perdigoto Cate Speake Carla J. Greenbaum Aïsha Callebaut Lut Overbergh Richard G. Kibbey Kevan C. Herold Eddie A. James Mark J. Mamula |
| author_sort | Mei-Ling Yang |
| collection | DOAJ |
| description | Post translational modifications are involved in the regulation of a number of proteins and can be themselves modified by the cellular environment. Here the authors implicate citrullination of glucokinase in autoimmune diabetes |
| first_indexed | 2024-04-12T22:43:17Z |
| format | Article |
| id | doaj.art-05c25682e0244aef9cf1385fd566a122 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-12T22:43:17Z |
| publishDate | 2022-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-05c25682e0244aef9cf1385fd566a1222022-12-22T03:13:38ZengNature PortfolioNature Communications2041-17232022-04-0113111110.1038/s41467-022-29512-0Citrullination of glucokinase is linked to autoimmune diabetesMei-Ling Yang0Sheryl Horstman1Renelle Gee2Perrin Guyer3TuKiet T. Lam4Jean Kanyo5Ana L. Perdigoto6Cate Speake7Carla J. Greenbaum8Aïsha Callebaut9Lut Overbergh10Richard G. Kibbey11Kevan C. Herold12Eddie A. James13Mark J. Mamula14Section of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale UniversityCenter for Translational Immunology, Benaroya Research Institute at Virginia MasonSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale UniversityCenter for Translational Immunology, Benaroya Research Institute at Virginia MasonDepartment of Molecular Biophysics & Biochemistry, Yale UniversityKeck MS & Proteomics Resource, WM Keck Foundation Biotechnology Resource LaboratorySection of Endocrinology, Department of Internal Medicine, Yale UniversityCenter for Interventional Immunology, Benaroya Research Institute at Virginia MasonCenter for Interventional Immunology, Benaroya Research Institute at Virginia MasonLaboratory for Clinical and Experimental Endocrinology, KU LeuvenLaboratory for Clinical and Experimental Endocrinology, KU LeuvenSection of Endocrinology, Department of Internal Medicine, Yale UniversitySection of Endocrinology, Department of Internal Medicine, Yale UniversityCenter for Translational Immunology, Benaroya Research Institute at Virginia MasonSection of Rheumatology, Allergy and Immunology, Department of Internal Medicine, Yale UniversityPost translational modifications are involved in the regulation of a number of proteins and can be themselves modified by the cellular environment. Here the authors implicate citrullination of glucokinase in autoimmune diabeteshttps://doi.org/10.1038/s41467-022-29512-0 |
| spellingShingle | Mei-Ling Yang Sheryl Horstman Renelle Gee Perrin Guyer TuKiet T. Lam Jean Kanyo Ana L. Perdigoto Cate Speake Carla J. Greenbaum Aïsha Callebaut Lut Overbergh Richard G. Kibbey Kevan C. Herold Eddie A. James Mark J. Mamula Citrullination of glucokinase is linked to autoimmune diabetes Nature Communications |
| title | Citrullination of glucokinase is linked to autoimmune diabetes |
| title_full | Citrullination of glucokinase is linked to autoimmune diabetes |
| title_fullStr | Citrullination of glucokinase is linked to autoimmune diabetes |
| title_full_unstemmed | Citrullination of glucokinase is linked to autoimmune diabetes |
| title_short | Citrullination of glucokinase is linked to autoimmune diabetes |
| title_sort | citrullination of glucokinase is linked to autoimmune diabetes |
| url | https://doi.org/10.1038/s41467-022-29512-0 |
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