Novel mRNA-specific effects of ribosome drop-off on translation rate and polysome profile.
The well established phenomenon of ribosome drop-off plays crucial roles in translational accuracy and nutrient starvation responses during protein translation. When cells are under stress conditions, such as amino acid starvation or aminoacyl-tRNA depletion due to a high level of recombinant protei...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5469512?pdf=render |