Novel mRNA-specific effects of ribosome drop-off on translation rate and polysome profile.

The well established phenomenon of ribosome drop-off plays crucial roles in translational accuracy and nutrient starvation responses during protein translation. When cells are under stress conditions, such as amino acid starvation or aminoacyl-tRNA depletion due to a high level of recombinant protei...

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Bibliographic Details
Main Authors: Pierre Bonnin, Norbert Kern, Neil T Young, Ian Stansfield, M Carmen Romano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5469512?pdf=render