Olmesartan medoxomil-loaded mixed micelles: Preparation, characterization and in-vitro evaluation

Olmesartan medoxomil-loaded mixed micelles: Preparation, characterization and in-vitro evaluation

Olmesartan medoxomil (OLM) is highly lipophilic in nature (log p = 4.31) which attributes to its low aqueous solubility contributing to its low bioavailability 25.6%. OLM was loaded into mixed micelles carriers in a trial to enhance its solubility, thus improving its oral bioavailability. OLM-loaded...

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Bibliographic Details
Main Authors: Mohamed A. El-Gendy, Mona I.A. El-Assal, Mina Ibrahim Tadros, Omaima N. El-Gazayerly
Format: Article
Language:English
Published: SpringerOpen 2017-12-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Olmesartan medoxomil
Mixed micelles
Thin film hydration
Reverse dialysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2314724516301844

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http://www.sciencedirect.com/science/article/pii/S2314724516301844

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