Understanding protein structural changes for oncogenic missense variants

Understanding and predicting the changes of protein structure and function upon mutation and their relationship to human health is a critical element to translate the genomic revolution into actionable interventions. Therefore, it is pertinent to explore how mutations result in structural changes le...

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Bibliographic Details
Main Authors: Rolando Hernandez, Julio C. Facelli
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021001183