All-Atom Molecular Dynamics Investigations on the Interactions between D2 Subunit Dopamine Receptors and Three <sup>11</sup>C-Labeled Radiopharmaceutical Ligands

All-Atom Molecular Dynamics Investigations on the Interactions between D2 Subunit Dopamine Receptors and Three <sup>11</sup>C-Labeled Radiopharmaceutical Ligands

The D2 subunit dopamine receptor represents a key factor in modulating dopamine release. Moreover, the investigated radiopharmaceutical ligands used in positron emission tomography imaging techniques are known to bind D2 receptors, allowing for dopaminergic pathways quantification in the living huma...

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Bibliographic Details
Main Authors: Sanda Nastasia Moldovean, Diana-Gabriela Timaru, Vasile Chiş
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine receptors
D2 subunit
molecular docking
molecular dynamics
interaction energies
ligand binding
Online Access:https://www.mdpi.com/1422-0067/23/4/2005

Internet

https://www.mdpi.com/1422-0067/23/4/2005

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