Transcriptomic signatures of individual cell types in cerebral cavernous malformation

Transcriptomic signatures of individual cell types in cerebral cavernous malformation

Abstract Cerebral cavernous malformation (CCM) is a hemorrhagic neurovascular disease with no currently available therapeutics. Prior evidence suggests that different cell types may play a role in CCM pathogenesis. The contribution of each cell type to the dysfunctional cellular crosstalk remains un...

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Main Authors: Ying Li, Romuald Girard, Abhinav Srinath, Diana Vera Cruz, Cezary Ciszewski, Chang Chen, Rhonda Lightle, Sharbel Romanos, Je Yeong Sone, Thomas Moore, Dorothy DeBiasse, Agnieszka Stadnik, Justine J. Lee, Robert Shenkar, Janne Koskimäki, Miguel A. Lopez-Ramirez, Douglas A. Marchuk, Mark H. Ginsberg, Mark L. Kahn, Changbin Shi, Issam A. Awad
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
Cerebral cavernous malformation
VEGFA/VEGFR2
Transcriptome
Cell–cell interaction
Online Access:https://doi.org/10.1186/s12964-023-01301-2

Internet

https://doi.org/10.1186/s12964-023-01301-2

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