Turning 21: Induction of miR-21 as a key switch in the inflammatory response

miR-21 is one of the most highly expressed members of the small non-coding microRNA family in many mammalian cell types. Its expression is further enhanced in many diseased states including solid tumors, cardiac injury and inflamed tissue. Whilst the induction of miR-21 by inflammatory stimuli cells...

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Bibliographic Details
Main Author: Frederick J Sheedy
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00019/full