TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application

TNFα priming through its interaction with TNFR2 enhances endothelial progenitor cell immunosuppressive effect: new hope for their widespread clinical application

Abstract Background Bone marrow derived endothelial progenitor cells (EPCs) are immature endothelial cells (ECs) involved in neo-angiogenesis and endothelial homeostasis and are considered as a circulating reservoir for endothelial repair. Many studies showed that EPCs from patients with cardiovascu...

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Bibliographic Details
Main Authors: Mahsa Nouri Barkestani, Sara Shamdani, Mazdak Afshar Bakshloo, Nassim Arouche, Bijan Bambai, Georges Uzan, Sina Naserian
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cell Communication and Signaling
Subjects:
Endothelial progenitor cells (EPCs)
Endothelial colony forming cells (ECFCs)
T cells
Immunomodulation
TNFα-TNFR2 signaling pathway
TNFα priming
Online Access:https://doi.org/10.1186/s12964-020-00683-x

Internet

https://doi.org/10.1186/s12964-020-00683-x

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