Simple Evaluation of Clinical Situation and Subtypes of Pediatric Hemophagocytic Lymphohistiocytosis by Cytokine Patterns

Simple Evaluation of Clinical Situation and Subtypes of Pediatric Hemophagocytic Lymphohistiocytosis by Cytokine Patterns

BackgroundHemophagocytic lymphohistiocytosis (HLH) is a rapidly fatal disease caused by immune dysregulation. Early initiation of treatment is imperative for saving lives. However, a laboratory approach that could be used to quickly evaluate the HLH subtype and clinical situation is lacking. Our pre...

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Bibliographic Details
Main Authors: Xiao-Jun Xu, Ze-Bin Luo, Hua Song, Wei-Qun Xu, Jan-Inge Henter, Ning Zhao, Meng-Hui Wu, Yong-Min Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
hemophagocytic lymphohistiocytosis
cytokines
interleukin-10
interferon-gamma
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.850443/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.850443/full

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