CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1
Abstract Some patients with polycystic ovarian syndrome (PCOS) suffered from metabolic syndrome (MetS) including dyslipidemia, hyperinsulinism, but the underlying mechanism is unclear. Although C-terminal Binding Protein 1 (CTBP1) is a transcriptional co-repressor frequently involved in hormone secr...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-024-06857-4 |