Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet

Abstract Obesity is a modifiable risk factor in cancer development, especially for gastrointestinal cancer. While the etiology of colorectal cancer is well characterized by the adenoma-carcinoma sequence, it remains unclear how obesity influences colorectal cancer development. Dietary components of...

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Main Authors: Mathilde Meyenberg, Anna Hakobyan, Nikolina Papac-Milicevic, Laura Göderle, Franziska L. Langner, Mateo Markovic, Ji-Hyun Lee, Bon-Kyoung Koo, Georg A. Busslinger, Israel Tojal da Silva, Christoph J. Binder, Jörg Menche, Joanna I. Loizou
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41123-3

Internet

https://doi.org/10.1038/s41598-023-41123-3

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