Rational drug repurposing for alzheimer’s treatment using in-silico ligand and structure-based approaches

Rational drug repurposing for alzheimer’s treatment using in-silico ligand and structure-based approaches

Abstract Alzheimer’s disease is a devastating neurodegenerative disorder characterized by memory loss and cognitive decline. New AD treatments are essential, and drug repositioning is a promising approach. In this study, we combined ligand-based and structure-based approaches to identify potential c...

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Bibliographic Details
Main Authors: Karishma Rathi, Ravindra Wavhale, Ritesh Bhole, Vaishali Undale, Somdatta Chaudhari
Format: Article
Language:English
Published: Universidade de São Paulo 2024-02-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Alzheimer’s disease.structure-based screening
ligand-based screening.FDA approved drugs
Docking
Swiss similarity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502024000100313&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502024000100313&lng=en&tlng=en

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