Clathrin-independent but dynamin-dependent mechanisms mediate Ca2+-triggered endocytosis of the glutamate GluK2 receptor upon excitotoxicity
We first explore the features of GluK2 endocytosis during kainate excitotoxicity and then explore the role of Ca2+ in the regulation of GluK2 endocytosis. The roles of Ca2+ were examined by treating cells with Ca2+ inhibitors or chelators. Surface biotinylation was used to examine the surface locali...
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Format: | Article |
Language: | English |
Published: |
IMR Press
2020-09-01
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Series: | Journal of Integrative Neuroscience |
Subjects: | |
Online Access: | https://jin.imrpress.com/fileup/1757-448X/PDF/1601428912820-662208988.pdf |