Clathrin-independent but dynamin-dependent mechanisms mediate Ca2+-triggered endocytosis of the glutamate GluK2 receptor upon excitotoxicity

We first explore the features of GluK2 endocytosis during kainate excitotoxicity and then explore the role of Ca2+ in the regulation of GluK2 endocytosis. The roles of Ca2+ were examined by treating cells with Ca2+ inhibitors or chelators. Surface biotinylation was used to examine the surface locali...

Full description

Bibliographic Details
Main Author: Jing-Jing Du, Lu Yan, Wei Zhang, Hao Xu, Qiu-Ju Zhu
Format: Article
Language:English
Published: IMR Press 2020-09-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://jin.imrpress.com/fileup/1757-448X/PDF/1601428912820-662208988.pdf