Together Intra-Tumor Hypoxia and Macrophagic Immunity Are Driven Worst Outcome in Pediatric High-Grade Osteosarcomas

Together Intra-Tumor Hypoxia and Macrophagic Immunity Are Driven Worst Outcome in Pediatric High-Grade Osteosarcomas

Background: Osteosarcomas (OTS) represent the most common primary bone cancer diagnosed in adolescents and young adults. Despite remarkable advances, there are no objective molecular or imaging markers able to predict an OTS outcome at diagnosis. Focusing on biomarkers contributing broadly to treatm...

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Bibliographic Details
Main Authors: Charlotte Nazon, Marina Pierrevelcin, Thibault Willaume, Benoît Lhermitte, Noelle Weingertner, Antonio Di Marco, Laurent Bund, Florence Vincent, Guillaume Bierry, Anne Gomez-Brouchet, Françoise Redini, Nathalie Gaspar, Monique Dontenwill, Natacha Entz-Werle
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
osteosarcoma
pediatric
biomarkers
hypoxia
macrophages
magnetic resonance imaging
Online Access:https://www.mdpi.com/2072-6694/14/6/1482

Internet

https://www.mdpi.com/2072-6694/14/6/1482

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