A novel NKp80-based strategy for universal identification of normal, reactive and tumor/clonal natural killer-cells in blood

A novel NKp80-based strategy for universal identification of normal, reactive and tumor/clonal natural killer-cells in blood

PurposeNatural killer (NK) cells are traditionally identified by flow cytometry using a combination of markers (CD16/CD56/CD3), because a specific NK-cell marker is still missing. Here we investigated the utility of CD314, CD335 and NKp80, compared to CD16/CD56/CD3, for more robust identification of...

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Main Authors: F. Javier Morán-Plata, Noemí Muñoz-García, María González-González, Julio Pozo, Sonia Carretero-Domínguez, Sheila Mateos, Susana Barrena, Moncef Belhassen-García, Catarina Lau, Maria Dos Anjos Teixeira, Ana Helena Santos, Ana Yeguas, Ana Balanzategui, Alejandro Martín García-Sancho, Alberto Orfao, Julia Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-07-01
Series:Frontiers in Immunology
Subjects:
NKp80
NK-cells
NK-cell markers
NK-cell gating strategy
CLPD-NK/NK-LGLL
NK-cell clonality
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423689/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1423689/full

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