EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

Abstract Activation of regulatory elements is thought to be inversely correlated with DNA methylation levels. However, it is difficult to determine whether DNA methylation is compatible with chromatin accessibility or transcription factor (TF) binding if assays are performed separately. We developed...

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Bibliographic Details
Main Authors: Priscillia Lhoumaud, Gunjan Sethia, Franco Izzo, Theodore Sakellaropoulos, Valentina Snetkova, Simon Vidal, Sana Badri, Macintosh Cornwell, Dafne Campigli Di Giammartino, Kyu-Tae Kim, Effie Apostolou, Matthias Stadtfeld, Dan Avi Landau, Jane Skok
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Subjects:
DNA methylation
Chromatin accessibility
ChIP
ATAC
CTCF
KLF4
Online Access:http://link.springer.com/article/10.1186/s13059-019-1853-6

Internet

http://link.springer.com/article/10.1186/s13059-019-1853-6

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