Pharmacological Evaluation of Total Alkaloids from Nux Vomica: Effect of Reducing Strychnine Contents

Pharmacological Evaluation of Total Alkaloids from Nux Vomica: Effect of Reducing Strychnine Contents

The aim of the study was to investigate the possibility of improving the therapeutic efficacy of the total alkaloid fraction (TAF) extracted from processed nux vomica by reducing the strychnine contents. Most strychnine was removed from TAF to obtain the modified total alkaloid fraction (MTAF). The...

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Bibliographic Details
Main Authors: Jun Chen, Yange Qu, Dongyue Wang, Pei Peng, Hao Cai, Ying Gao, Zhipeng Chen, Baochang Cai
Format: Article
Language:English
Published: MDPI AG 2014-04-01
Series:Molecules
Subjects:
Strychnos nux-vomica L.
total alkaloids
antitumor
analgesic
anti-inflammatory
oral administration
pharmacokinetics
acute toxicity
Online Access:http://www.mdpi.com/1420-3049/19/4/4395

Internet

http://www.mdpi.com/1420-3049/19/4/4395

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