Unveiling Epigenetic Vulnerabilities in Triple-Negative Breast Cancer through 3D Organoid Drug Screening

Unveiling Epigenetic Vulnerabilities in Triple-Negative Breast Cancer through 3D Organoid Drug Screening

Triple-negative breast cancer (TNBC) poses a therapeutic challenge due to its aggressive nature and lack of targeted therapies. Epigenetic modifications contribute to TNBC tumorigenesis and drug resistance, offering potential therapeutic targets. Recent advancements in three-dimensional (3D) organoi...

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Bibliographic Details
Main Authors: Xinxin Rao, Zhibin Qiao, Yang Yang, Yun Deng, Zhen Zhang, Xiaoli Yu, Xiaomao Guo
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceuticals
Subjects:
triple-negative breast cancer
patient-derived organoids
drug screening
epigenetic inhibitors
treatment
Online Access:https://www.mdpi.com/1424-8247/17/2/225

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https://www.mdpi.com/1424-8247/17/2/225

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