Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish

Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish

Background: We are using genetics to identify genes specifically involved in hearing regeneration. In a large-scale genetic screening, we identified mgat5a, a gene in the N-glycosylation biosynthesis pathway whose activity negatively impacts hair cell regeneration. Methods: We used a combination of...

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Bibliographic Details
Main Authors: Wuhong Pei, Sunny C. Huang, Lisha Xu, Kade Pettie, María Laura Ceci, Mario Sánchez, Miguel L. Allende, Shawn M. Burgess
Format: Article
Language:English
Published: SpringerOpen 2016-01-01
Series:Cell Regeneration
Subjects:
Zebrafish
CRISPR/Cas9
mgat5a
N-glycosylation
Regeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2045976917300032

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http://www.sciencedirect.com/science/article/pii/S2045976917300032

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