Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery

Identification of Novel Potential VEGFR-2 Inhibitors Using a Combination of Computational Methods for Drug Discovery

The vascular endothelial growth factor receptor 2 (VEGFR-2) is largely recognized as a potent therapeutic molecular target for the development of angiogenesis-related tumor treatment. Tumor growth, metastasis and multidrug resistance highly depends on the angiogenesis and drug discovery of the poten...

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Bibliographic Details
Main Authors: Mohammad M. Al-Sanea, Garri Chilingaryan, Narek Abelyan, Arsen Sargsyan, Sargis Hovhannisyan, Hayk Gasparyan, Smbat Gevorgyan, Sarah Albogami, Mohammed M. Ghoneim, Ahmed K. Farag, Ahmed A. B. Mohamed, Ashraf K. El-Damasy
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
VEGFR2
tivozanib
virtual screening
drug discovery
molecular dynamics simulations
Online Access:https://www.mdpi.com/2075-1729/11/10/1070

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https://www.mdpi.com/2075-1729/11/10/1070

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