Automated GMP-Compliant Production of [<sup>68</sup>Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans

Automated GMP-Compliant Production of [<sup>68</sup>Ga]Ga-DO3A-Tuna-2 for PET Microdosing Studies of the Glucagon Receptor in Humans

<b>Introduction</b>: [<sup>68</sup>Ga]Ga-DO3A-VS-Cys<sup>40</sup>-Tuna-2 (previously published as [<sup>68</sup>Ga]Ga-DO3A-VS-Cys<sup>40</sup>-S01-GCG) has shown high-affinity specific binding to the glucagon receptor (GCGR) in vitro and in...

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Bibliographic Details
Main Authors: Michael Wagner, Johan G. Doverfjord, Joachim Tillner, Gunnar Antoni, Torsten Haack, Martin Bossart, Iina Laitinen, Lars Johansson, Stefan Pierrou, Olof Eriksson, Irina Velikyan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceuticals
Subjects:
glucagon receptor
diabetes
GMP
Gallium-68
automation
radiopharmaceuticals
Online Access:https://www.mdpi.com/1424-8247/13/8/176

Internet

https://www.mdpi.com/1424-8247/13/8/176

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