Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression

Nuclear Receptor Binding Protein 2 Is Downregulated in Medulloblastoma, and Reduces Tumor Cell Survival upon Overexpression

Pseudokinases, comprising 10% of the human kinome, are emerging as regulators of canonical kinases and their functions are starting to be defined. We previously identified the pseudokinase Nuclear Receptor Binding Protein 2 (NRBP2) in a screen for genes regulated during neural differentiation. Durin...

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Bibliographic Details
Main Authors: Anqi Xiong, Ananya Roy, Argyris Spyrou, Holger Weishaupt, Voichita D. Marinescu, Tommie Olofsson, Ola Hermanson, Fredrik J. Swartling, Karin Forsberg-Nilsson
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
brain tumor
pseudokinase
NRBP
pediatric cancer
apoptosis
Online Access:https://www.mdpi.com/2072-6694/12/6/1483

Internet

https://www.mdpi.com/2072-6694/12/6/1483

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