Characterization of G6PD genotypes and phenotypes on the northwestern Thailand-Myanmar border.

Characterization of G6PD genotypes and phenotypes on the northwestern Thailand-Myanmar border.

Mutations in the glucose-6-phosphate dehydrogenase (G6PD) gene result in red blood cells with increased susceptibility to oxidative damage. Significant haemolysis can be caused by primaquine and other 8-aminoquinoline antimalarials used for the radical treatment of Plasmodium vivax malaria. The dist...

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Bibliographic Details
Main Authors: Germana Bancone, Cindy S Chu, Raweewan Somsakchaicharoen, Nongnud Chowwiwat, Daniel M Parker, Prakaykaew Charunwatthana, Nicholas J White, François H Nosten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275285?pdf=render

Internet

http://europepmc.org/articles/PMC4275285?pdf=render

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