Predicting lymph node metastasis from primary tumor histology and clinicopathologic factors in colorectal cancer using deep learning

Abstract Background Presence of lymph node metastasis (LNM) influences prognosis and clinical decision-making in colorectal cancer. However, detection of LNM is variable and depends on a number of external factors. Deep learning has shown success in computational pathology, but has struggled to boos...

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Bibliographic Details
Main Authors: Justin D. Krogue, Shekoofeh Azizi, Fraser Tan, Isabelle Flament-Auvigne, Trissia Brown, Markus Plass, Robert Reihs, Heimo Müller, Kurt Zatloukal, Pema Richeson, Greg S. Corrado, Lily H. Peng, Craig H. Mermel, Yun Liu, Po-Hsuan Cameron Chen, Saurabh Gombar, Thomas Montine, Jeanne Shen, David F. Steiner, Ellery Wulczyn
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-023-00282-0