miR-135a-5p overexpression in peripheral blood-derived exosomes mediates vascular injury in type 2 diabetes patients

miR-135a-5p overexpression in peripheral blood-derived exosomes mediates vascular injury in type 2 diabetes patients

ObjectiveDiabetes pathology relies on exosomes (Exos). This study investigated how peripheral blood Exo-containing microRNAs (miRNAs) cause vascular injury in type 2 diabetes (T2D).MethodsWe removed DEmiRNA from T2D chip data from the GEO database. We isolated Exo from 15 peripheral blood samples fr...

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Bibliographic Details
Main Authors: Kangling Xie, Cui Li, Mingzhu Wang, Siqian Fu, Ying Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Endocrinology
Subjects:
peripheral blood-derived exosomes
microRNA-135a-3p
ErbB
ATM
Type 2 diabetes
vascular injury
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1035029/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1035029/full

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