Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells

Anticancer Effect of Cathelicidin LL-37, Protegrin PG-1, Nerve Growth Factor NGF, and Temozolomide: Impact on the Mitochondrial Metabolism, Clonogenic Potential, and Migration of Human U251 Glioma Cells

Glioblastoma (GBM) is one of the most aggressive and lethal malignancy of the central nervous system. Temozolomide is the standard of care for gliomas, frequently results in resistance to drug and tumor recurrence. Therefore, further research is required for the development of effective drugs in ord...

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Bibliographic Details
Main Authors: Alexandr N. Chernov, Tatiana A. Filatenkova, Ruslan I. Glushakov, Alexandra S. Buntovskaya, Diana A. Alaverdian, Anna N. Tsapieva, Alexandr V. Kim, Evgeniy V. Fedorov, Sofia S. Skliar, Marina V. Matsko, Elvira S. Galimova, Olga V. Shamova
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
human glioma U251
cathelicidin LL-37
protegrin PG-1
nerve growth factor NGF
temozolomide
migration
Online Access:https://www.mdpi.com/1420-3049/27/15/4988

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https://www.mdpi.com/1420-3049/27/15/4988

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