The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure

The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure

Oncostatin M (OSM), a member of the interleukin-6 family, functions as a major mediator of cardiomyocyte remodeling under pathological conditions. Its involvement in a variety of human cardiac diseases such as aortic stenosis, myocardial infarction, myocarditis, cardiac sarcoidosis, and various card...

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Bibliographic Details
Main Authors: Thomas Kubin, Praveen Gajawada, Peter Bramlage, Stefan Hein, Benedikt Berge, Ayse Cetinkaya, Heiko Burger, Markus Schönburg, Wolfgang Schaper, Yeong-Hoon Choi, Manfred Richter
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
oncostatin M receptor
leukemia inhibitory factor receptor
gp130
interleukin-6
cardiomyocyte
inflammation
Online Access:https://www.mdpi.com/1422-0067/23/3/1811

Internet

https://www.mdpi.com/1422-0067/23/3/1811

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