Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET

Feasibility of imaging synaptic density in the human spinal cord using [11C]UCB-J PET

Abstract Purpose Neuronal damage and synapse loss in the spinal cord (SC) have been implicated in spinal cord injury (SCI) and neurodegenerative disorders such as Amyotrophic Lateral Sclerosis (ALS). Current standards of diagnosis for SCI include CT or MRI imaging to evaluate injury severity. The cu...

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Bibliographic Details
Main Authors: Samantha Rossano, Takuya Toyonaga, Jason Bini, Nabeel Nabulsi, Jim Ropchan, Zhengxin Cai, Yiyun Huang, Richard E. Carson
Format: Article
Language:English
Published: SpringerOpen 2022-05-01
Series:EJNMMI Physics
Subjects:
Synaptic density
SV2A
Spinal cord
PET
Online Access:https://doi.org/10.1186/s40658-022-00464-0

Internet

https://doi.org/10.1186/s40658-022-00464-0

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