Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model

Older individuals are at higher risk of SARS-CoV-2 infection and severe outcomes, but the underlying mechanisms are incompletely understood. In addition, how age modulates SARS-CoV-2 re-infection and vaccine breakthrough infections remain largely unexplored. Here, we investigated age-associated SARS...

Full description

Bibliographic Details
Main Authors: Yanxia Chen, Can Li, Feifei Liu, Zhanhong Ye, Wenchen Song, Andrew C. Y. Lee, Huiping Shuai, Lu Lu, Kelvin Kai-Wang To, Jasper Fuk-Woo Chan, Anna Jinxia Zhang, Hin Chu, Kwok-Yung Yuen
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:http://dx.doi.org/10.1080/22221751.2022.2026741