Facile and general electrochemical deuteration of unactivated alkyl halides

Facile and general electrochemical deuteration of unactivated alkyl halides

Deuterium-labelled compounds are useful for mechanistic studies and pharmaceutical science, but syntheses are not trivial. Here, the authors report deuteration of unactivated alkyl (pseudo)halides driven by electrochemical force, using deuterium oxide as the source of the isotope.

Bibliographic Details
Main Authors: Pengfei Li, Chengcheng Guo, Siyi Wang, Dengke Ma, Tian Feng, Yanwei Wang, Youai Qiu
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31435-9

Internet

https://doi.org/10.1038/s41467-022-31435-9

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