Differential Activation of pERK1/2 and c-Fos Following Injury to Different Regions of Primary Sensory Neuron

Nerve injury causes hyperexcitability of the dorsal root ganglion (DRG) and spinal dorsal horn (DH) neurons, which results in neuropathic pain. We have previously demonstrated that partial dorsal rhizotomy (PDR) produced less severe pain-like behavior than chronic constriction injury (CCI) or chroni...

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Bibliographic Details
Main Authors: Bei Miao, Hongyu Yao, Peng Chen, Xue-Jun Song
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/5/752