The novel role of platelet-activating factor in protecting mice against lipopolysaccharide-induced endotoxic shock.

BACKGROUND:Platelet-activating factor (PAF) has been long believed to be associated with many pathophysiological processes during septic shock. Here we present novel activities for PAF in protecting mice against LPS-mediated endotoxic shock. PRINCIPAL FINDINGS:In vivo PAF treatment immediately after...

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Main Authors: Young-Il Jeong, In Duk Jung, Chang-Min Lee, Jeong Hyun Chang, Sung Hak Chun, Kyung Tae Noh, Soo Kyung Jeong, Yong Kyoo Shin, Won Suk Lee, Mi Sun Kang, Sang-Yull Lee, Jae-Dong Lee, Yeong-Min Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2714981?pdf=render