Case Report: A novel TP53 mutation in a patient with quadruple wild-type gastrointestinal stromal tumor

Case Report: A novel TP53 mutation in a patient with quadruple wild-type gastrointestinal stromal tumor

In this report, we present a case study of a 64-year-old female who was diagnosed with gastrointestinal stromal tumors (GISTs) and subsequently developed liver metastases despite undergoing radical resection. Next-generation sequencing (NGS) assays indicated that the tumor lacked KIT/PDGFRA/SDH/RAS-...

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Bibliographic Details
Main Authors: Yuhong Chen, Junyong Chen, Liansheng Long, Leng Han, Xiaohui Mi, Yanfang Song, Huanqing Cheng, Yanrui Zhang, Liyang Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Oncology
Subjects:
case report
quadruple WT GIST
next-generation sequencing
TP53 mutation
p53-targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1260706/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1260706/full

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