The vulnerability of radical SAM enzymes to oxidants and soft metals

Radical S-adenosylmethionine enzymes (RSEs) drive diverse biological processes by catalyzing chemically difficult reactions. Each of these enzymes uses a solvent-exposed [4Fe–4S] cluster to coordinate and cleave its SAM co-reactant. This cluster is destroyed during oxic handling, forcing investigato...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Sanjay Kumar Rohaun, James A. Imlay
स्वरूप: लेख
भाषा:English
प्रकाशित: Elsevier 2022-11-01
श्रृंखला:Redox Biology
विषय:
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2213231722002671