Development and clinical validation of CT-based regional modified Centiloid method for amyloid PET

Development and clinical validation of CT-based regional modified Centiloid method for amyloid PET

Abstract Background The standard Centiloid (CL) method was proposed to harmonize and quantify global 18F-labeled amyloid beta (Aβ) PET ligands using MRI as an anatomical reference. However, there is need for harmonizing and quantifying regional Aβ uptakes between ligands using CT as an anatomical re...

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Bibliographic Details
Main Authors: Soo-Jong Kim, Hongki Ham, Yu Hyun Park, Yeong Sim Choe, Young Ju Kim, Hyemin Jang, Duk L. Na, Hee Jin Kim, Seung Hwan Moon, Sang Won Seo
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Amyloid PET
CT
Regional modified Centiloid
Clinical validation
Online Access:https://doi.org/10.1186/s13195-022-01099-0

Internet

https://doi.org/10.1186/s13195-022-01099-0

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