Evaluation of Trace Elements in Augmentation of Statin-Induced Cytotoxicity in Uremic Serum-Exposed Human Rhabdomyosarcoma Cells

Evaluation of Trace Elements in Augmentation of Statin-Induced Cytotoxicity in Uremic Serum-Exposed Human Rhabdomyosarcoma Cells

Patients with end-stage kidney disease (ESKD) are at higher risk for rhabdomyolysis induced by statin than patients with normal kidney function. Previously, we showed that this increase in the severity of statin-induced rhabdomyolysis was partly due to uremic toxins. However, changes in the quantity...

Full description

Bibliographic Details
Main Authors: Hitoshi Uchiyama, Masayuki Tsujimoto, Naomi Shimada, Koji Tsutsui, Ayaka Nitta, Takuya Yoshida, Taku Furukubo, Satoshi Izumi, Tomoyuki Yamakawa, Hidehisa Tachiki, Tetsuya Minegaki, Kohshi Nishiguchi
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Toxins
Subjects:
end-stage kidney disease
uremic serum
simvastatin
cytotoxicity
zinc
rhabdomyolysis
Online Access:http://www.mdpi.com/2072-6651/10/2/53

Internet

http://www.mdpi.com/2072-6651/10/2/53

Similar Items